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The Big Bang Theory is an American television sitcom created by Chuck Lorre and Bill Prady, both of whom serve as executive producers on the series, along with Steven Molaro. The geekiness and intellect of the four men are contrasted for comic effect with Penny's social skills and common sense. The show is primarily centered on five characters living in Pasadena, California: Leonard Hofstadter and Sheldon Cooper, both physicists at Caltech, who share an apartment; Penny, a waitress and aspiring actress who later becomes a pharmaceutical representative and who lives across the hall; and Leonard and Sheldon's similarly geeky and socially awkward friends and co-workers, aerospace engineer Howard Wolowitz and astrophysicist Raj Koothrappali.Over time, supporting characters have been promoted to starring roles: Leslie Winkle, a physicist who dated Leonard and Howard; neuroscientist Amy Farrah Fowler, who joins the group after being matched to Sheldon on a dating website (and later becomes Sheldon's girlfriend and fiancée); Bernadette Rostenkowski, Howard's wife (previously his girlfriend), a microbiologist and former part-time waitress alongside Penny; Stuart Bloom, the cash-strapped owner of the comic book store the characters often visit; and Emily Sweeney, a dermatologist who dated Raj.

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The structure of the original unaired pilot was substantially different from the series' current form.

The only characters retained in both pilots were Leonard (Johnny Galecki) and Sheldon (Jim Parsons), who are named after Sheldon Leonard, a longtime figure in episodic television as producer, director and actor.

Althea (Vernee Watson) was a character featured in both pilots and the first series episode.

and Iris Bahr as Gilda, a scientist colleague and friend of the male characters.

Sheldon and Leonard meet Katie after she breaks up with a boyfriend and they invite her to share their apartment. Test audiences reacted negatively to Katie, but they liked Sheldon and Leonard.

The original pilot used Thomas Dolby's hit "She Blinded Me with Science" as its theme song.

Although the original pilot was not picked up, its creators were given an opportunity to retool it and produce a second pilot.

They brought in the remaining cast and retooled the show to its final format. The original unaired pilot never has officially been released, but it has circulated on the Internet.

On the evolution of the show, Chuck Lorre said, "We did the 'Big Bang Pilot' about two and a half years ago, and it sucked ...

but there were two remarkable things that worked perfectly, and that was Johnny and Jim.

We rewrote the thing entirely and then we were blessed with Kaley and Simon and Kunal." As to whether the world will ever see the original pilot on a future DVD release, Lorre said, "Wow, that would be something. Show your failures..." Production was halted on November 6, 2007, due to the Writers Guild of America strike.

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